Discoveries of new superconductors with high transition temperatures have been a perpetual drive of condensed matter physics. In this talk, I attempt to give an overview on recent advances in this vibrant area, with some of own stories squeezed in. We start from predictive designs of freestanding or supported superconducting monolayers that may exhibit high-Tc superconductivity, as well as low-dimensional systems that display exotic Ising, chiral, or p-wave superconductivity. On the mechanistic side, I will demonstrate how plasmonic excitations or pronounced correlation effects can enhance the superconductivity of iron-based superconductors, and predict designer substrates that may optimize the strain in La3Ni2O7 thin films for maximally enhanced Tc.